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Before 1752 botany was considered an ancillary subject to medicine and students of botany attended lectures at the University given by a professor of medicine.
In 1752 G.C. Oeder was appointed professor of botany by Royal decree. Originally Oeder was to have held a professorship in botany at the University, but opposition from academic quarters put an end to that. Instead the self-governing Royal Botanical Institution was established.
In 1753 Oeder proposed the publication of a Flora Danica with folio-sized pictures of all wild plants in Denmark. The aim was to popularize botany and in that way enhance the knowledge of the useful and harmful characters of the various plants.
The first part of the book was published in 1761 (ahead of time) and the last 113 years later in 1874.
Oeder was fired as editor in 1772 after the downfall of Struensee (Chr. VII's physician who was charged with plotting a palace coup), and replaced by the zoologist O.F. Müller. Following him 11 different botanists were in charge of publishing Flora Danica.
The plates appeared in a hand-painted edition and a "cheap" plain one. The bulk of the work - what one usually associates with Flora Danica- consists of 51 parts + 3 supplements, containing 3240 copper engraved plates.
To ensure that the work became known in all corners of the country free copies of the plain edition were given to the bishops, who distributed them to clergymen, grammar schools and educated persons. The recipients should in return "provide the Royal Botanical Institution or the Botanical Gardens with information of plants in their part of the country."
The project was supported financially by the Crown, which meant that a copy with 60 coloured plates could be put on the market for as little as 6 rix-dollars (subscription rate), and the plain edition for 4.
Flora Danica has no system of classification, which makes it a little difficult to work with at times, but in 1887 the botanist Johan Lange published a "Nomenclator Flora Danica...." that contains alphabetical, systematic and chronological lists of the plants in Flora Danica.
Actually Oeder was not the first to use the title Flora Danica. Another book by that name had been published in 1648 at the request of Chr. IV by Simon Paulli, doctor and botanist. That Flora Danica was a herbal describing plants of medical interest.
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